---
title: SDS - Envu Esplanade Herbicide - 241024
canonical: https://fernland.com.au/documents/322/
dateModified: 2026-08-03 01:14:14
summary: Safety Data Sheet
type: sds
---

# SDS - Envu Esplanade Herbicide - 241024

> Safety Data Sheet

SAFETY DATA SHEET
ESPLANADE HERBICIDE

Version
3.0
Revision Date:
04.10.2024
SDS Number:
11239657-00005
Date of last issue: 22.04.2024
Date of first issue: 07.07.2023
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SECTION 1: IDENTIFICATION
Product name : ESPLANADE HERBICIDE
Product code : Article/SKU: 86263459, 86282178, 87284603 UVP: 84105899
Specification: 102000023685

Manufacturer or supplier's details
Company : 2022 Environmental Science AU Pty Ltd

Address : Suite 2.06, Level 2, 737 Burwood Road
Hawthorn East, Australia 3123
Emergency telephone number :

Recommended use of the chemical and restrictions on use
Recommended use : Herbicide
Restrictions on use : Not applicable

SECTION 2. HAZARDS IDENTIFICATION
GHS Classification
Skin sensitisation : Category 1
Specific target organ toxicity -
repeated exposure
: Category 2 (Central nervous system)

GHS label elements
Hazard pictograms : [Exclamation mark and Health hazard pictograms]
Signal word : Warning
Hazard statements : H317 May cause an allergic skin reaction.
H373 May cause damage to organs (Central nervous system)
through prolonged or repeated exposure.
Precautionary statements :
Prevention:
P260 Do not breathe mist or vapours.

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P272 Contaminated work clothing should not be allowed out of
the workplace.
P280 Wear protective gloves.
Response:
P302 + P352 IF ON SKIN: Wash with plenty of water.
P314 Get medical advice/ attention if you feel unwell.
P321 Specific treatment (see supplemental first aid instructions
on this label).
P333 + P313 If skin irritation or rash occurs: Get medical ad vice/ attention.
P362 + P364 Take off contaminated clothing and wash it before
reuse.
Disposal:
P501 Dispose of contents/ container to an approved waste
disposal plant.

Other hazards which do not result in classification
None known.

SECTION 3. COMPOSITION/INFORMATION ON INGREDIENTS
Substance / Mixture : Mixture
Chemical nature : Suspension concentrate (=flowable concentrate)(SC)

Components
| Chemical name | CAS-No. | Concentration (% w/w) |
| :--- | :--- | :--- |
| Indaziflam | 950782-86-2 | >= 30 -= 0.036 - 2,000 mg/kg
Method: OECD Test Guideline 423
Remarks: Based on data from similar materials
Acute inhalation toxicity : LC50 (Rat): > 1 mg/l
Exposure time: 4 h
Test atmosphere: dust/mist
Method: OECD Test Guideline 403
Remarks: Based on data from similar materials
Acute dermal toxicity : LD50 (Rat): > 2,000 mg/kg
Method: OECD Test Guideline 402
Remarks: Based on data from similar materials
Propylene glycol:
Acute oral toxicity : LD50 (Rat): 22,000 mg/kg
Acute inhalation toxicity : LC50 (Rat): > 44.9 mg/l
Exposure time: 4 h
Test atmosphere: dust/mist
Acute dermal toxicity : LD50 (Rabbit): > 2,000 mg/kg
Assessment: The substance or mixture has no acute dermal
toxicity
1,2-Benzisothiazol-3(2H)-one:
Acute oral toxicity : LD50 (Rat, male): 450 mg/kg
Method: OECD Test Guideline 401
Acute inhalation toxicity : LC50 (Rat, male): 0.21 mg/l
Exposure time: 4 h
Test atmosphere: dust/mist
Method: OECD Test Guideline 403
Acute dermal toxicity : LD50 (Rat): > 2,000 mg/kg
Method: OECD Test Guideline 402
Assessment: The substance or mixture has no acute dermal
toxicity
Skin corrosion/irritation
Not classified based on available information.
Components:
Indaziflam:

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Species : Rabbit
Method : OECD Test Guideline 404
Result : No skin irritation
Remarks : Based on data from similar materials
Propylene glycol:
Species : Rabbit
Method : OECD Test Guideline 404
Result : No skin irritation
1,2-Benzisothiazol-3(2H)-one:
Result : Skin irritation
Serious eye damage/eye irritation
Not classified based on available information.
Components:
Indaziflam:
Species : Rabbit
Result : No eye irritation
Method : OECD Test Guideline 405
Remarks : Based on data from similar materials
Propylene glycol:
Species : Rabbit
Result : No eye irritation
Method : OECD Test Guideline 405
1,2-Benzisothiazol-3(2H)-one:
Species : Rabbit
Result : Irreversible effects on the eye
Respiratory or skin sensitisation
Skin sensitisation
May cause an allergic skin reaction.
Respiratory sensitisation
Not classified based on available information.
Components:
Indaziflam:
Test Type : Local lymph node assay (LLNA)
Exposure routes : Skin contact
Species : Mouse
Method : OECD Test Guideline 429
Result : negative

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Remarks : Based on data from similar materials
Propylene glycol:
Test Type : Maximisation Test
Exposure routes : Skin contact
Species : Guinea pig
Result : negative
1,2-Benzisothiazol-3(2H)-one:
Test Type : Maximisation Test
Exposure routes : Skin contact
Species : Guinea pig
Method : OECD Test Guideline 406
Result : positive
Assessment : Probability or evidence of high skin sensitisation rate in hu mans
Chronic toxicity
Germ cell mutagenicity
Not classified based on available information.
Components:
Indaziflam:
Genotoxicity in vitro : Test Type: Bacterial reverse mutation assay (AMES)
Method: OECD Test Guideline 471
Result: negative
Remarks: Based on data from similar materials
Test Type: In vitro mammalian cell gene mutation test
Method: OECD Test Guideline 476
Result: negative
Remarks: Based on data from similar materials
Test Type: Chromosome aberration test in vitro
Method: OECD Test Guideline 473
Result: negative
Remarks: Based on data from similar materials
Genotoxicity in vivo : Test Type: Mammalian erythrocyte micronucleus test (in vivo
cytogenetic assay)
Species: Mouse
Application Route: Intraperitoneal injection
Method: OECD Test Guideline 474
Result: negative
Remarks: Based on data from similar materials
Propylene glycol:

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Genotoxicity in vitro : Test Type: Bacterial reverse mutation assay (AMES)
Result: negative
Test Type: Chromosome aberration test in vitro
Method: OECD Test Guideline 473
Result: negative
Genotoxicity in vivo : Test Type: Mammalian erythrocyte micronucleus test (in vivo
cytogenetic assay)
Species: Mouse
Application Route: Intraperitoneal injection
Result: negative
1,2-Benzisothiazol-3(2H)-one:
Genotoxicity in vitro : Test Type: Bacterial reverse mutation assay (AMES)
Method: OECD Test Guideline 471
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Method: OECD Test Guideline 476
Result: negative
Test Type: Chromosome aberration test in vitro
Method: OECD Test Guideline 473
Result: positive
Genotoxicity in vivo : Test Type: Unscheduled DNA synthesis (UDS) test with
mammalian liver cells in vivo
Species: Rat
Application Route: Ingestion
Method: OECD Test Guideline 486
Result: negative
Carcinogenicity
Not classified based on available information.
Components:
Indaziflam:
Species : Mouse
Application Route : Ingestion
Exposure time : 78 weeks
Method : OECD Test Guideline 451
Result : negative
Propylene glycol:
Species : Rat
Application Route : Ingestion
Exposure time : 2 Years
Result : negative

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Reproductive toxicity
Not classified based on available information.
Components:
Indaziflam:
Effects on fertility : Test Type: Two-generation reproduction toxicity study
Species: Rat
Application Route: Ingestion
Method: OECD Test Guideline 416
Result: negative
Remarks: Based on data from similar materials
Effects on foetal develop ment
: Test Type: Embryo-foetal development
Species: Rat
Application Route: Ingestion
Method: OECD Test Guideline 414
Result: negative
Remarks: Based on data from similar materials
Propylene glycol:
Effects on fertility : Test Type: Two-generation reproduction toxicity study
Species: Mouse
Application Route: Ingestion
Result: negative
Effects on foetal develop ment
: Test Type: Embryo-foetal development
Species: Mouse
Application Route: Ingestion
Result: negative
1,2-Benzisothiazol-3(2H)-one:
Effects on fertility : Test Type: Fertility/early embryonic development
Species: Rat
Application Route: Ingestion
Method: OPPTS 870.3800
Result: negative
STOT - single exposure
Not classified based on available information.
STOT - repeated exposure
May cause damage to organs (Central nervous system) through prolonged or repeated exposure.
Components:
Indaziflam:
Exposure routes : Ingestion
Target Organs : Central nervous system
Assessment : Shown to produce significant health effects in animals at con centrations of >10 to 100 mg/kg bw.

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1,2-Benzisothiazol-3(2H)-one:
Assessment : No significant health effects observed in animals at concentra tions of 100 mg/kg bw or less.
Repeated dose toxicity
Components:
Indaziflam:
Species : Dog
LOAEL : > 2.5 - 25 mg/kg
Application Route : Ingestion
Exposure time : 1 yr
Method : OECD Test Guideline 452
Remarks : Based on data from similar materials
Species : Rat
NOAEL : > 600 mg/kg
Application Route : Skin contact
Exposure time : 28 Days
Method : OECD Test Guideline 410
Remarks : Based on data from similar materials
Propylene glycol:
Species : Rat, male
NOAEL : >= 1,700 mg/kg
Application Route : Ingestion
Exposure time : 2 yr
1,2-Benzisothiazol-3(2H)-one:
Species : Dog
NOAEL : 5 mg/kg
LOAEL : 20 mg/kg
Application Route : Ingestion
Exposure time : 90 Days
Method : Directive 67/548/EEC, Annex, B.27
Aspiration toxicity
Not classified based on available information.

SECTION 12. ECOLOGICAL INFORMATION
Ecotoxicity
Product:
Toxicity to fish : LC50 (Lepomis macrochirus (Bluegill sunfish)): 0.849 mg/l
Exposure time: 96 h

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Toxicity to daphnia and other
aquatic invertebrates
: EC50 (Daphnia magna (Water flea)): > 100 mg/l
Exposure time: 48 h
Toxicity to algae/aquatic
plants
: EC50 (Lemna gibba (gibbous duckweed)): 0.0001509 mg/l
Exposure time: 168 h
Test Type: Growth inhibition
EC50 (Raphidocelis subcapitata (freshwater green alga)):
0.094 mg/l
Exposure time: 72 h
Test Type: Growth inhibition
Remarks: Based on data from similar materials
Ecotoxicology Assessment
Toxicity Data on Soil : Very toxic to the soil environment.
Components:
Indaziflam:
Toxicity to fish : LC50 (Oncorhynchus mykiss (rainbow trout)): > 0.1 - 1 mg/l
Exposure time: 96 h
Method: OECD Test Guideline 203
Remarks: Based on data from similar materials
Toxicity to daphnia and other
aquatic invertebrates
: EC50 (Mysidopsis bahia (opossum shrimp)): 1.5 mg/l
Exposure time: 48 h
Method: US-EPA OPPTS 850.1035
Toxicity to algae/aquatic
plants
: ErC50 (Lemna gibba (gibbous duckweed)): > 0.0001 - 0.001
mg/l
Exposure time: 7 d
Method: OECD Test Guideline 221
Remarks: Based on data from similar materials
NOEC: > 0.000001 - 0.00001 mg/l
Exposure time: 70 d
Method: OECD Test Guideline 221
Remarks: Based on data from similar materials
Toxicity to fish (Chronic tox icity)
: NOEC (Pimephales promelas (fathead minnow)): > 0.1 - 1
mg/l
Exposure time: 35 d
Method: OECD Test Guideline 210
Remarks: Based on data from similar materials
Toxicity to daphnia and other
aquatic invertebrates (Chron ic toxicity)
: NOEC (Mysidopsis bahia (opossum shrimp)): 0.12 mg/l
Exposure time: 28 d
Toxicity to microorganisms : NOEC (activated sludge): > 1 mg/l
Exposure time: 3 h

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Method: OECD Test Guideline 209
Remarks: Based on data from similar materials
Propylene glycol:
Toxicity to fish : LC50 (Oncorhynchus mykiss (rainbow trout)): 40,613 mg/l
Exposure time: 96 h
Toxicity to daphnia and other
aquatic invertebrates
: EC50 (Ceriodaphnia dubia (water flea)): 18,340 mg/l
Exposure time: 48 h
Toxicity to algae/aquatic
plants
: ErC50 (Skeletonema costatum (marine diatom)): 19,300 mg/l
Exposure time: 72 h
Method: OECD Test Guideline 201
Toxicity to daphnia and other
aquatic invertebrates (Chron ic toxicity)
: NOEC (Ceriodaphnia dubia (water flea)): 13,020 mg/l
Exposure time: 7 d
Toxicity to microorganisms : NOEC (Pseudomonas putida): > 20,000 mg/l
Exposure time: 18 h
1,2-Benzisothiazol-3(2H)-one:
Toxicity to fish : LC50 (Oncorhynchus mykiss (rainbow trout)): 0.74 mg/l
Exposure time: 96 h
Toxicity to daphnia and other
aquatic invertebrates
: EC50 (Daphnia magna (Water flea)): 2.24 mg/l
Exposure time: 48 h
Toxicity to algae/aquatic
plants
: ErC50 (Pseudokirchneriella subcapitata (green algae)):
0.1087 mg/l
Exposure time: 24 h
EC10 (Pseudokirchneriella subcapitata (green algae)): 0.0268
mg/l
Exposure time: 24 h
Toxicity to fish (Chronic tox icity)
: NOEC (Pimephales promelas (fathead minnow)): 0.28 mg/l
Exposure time: 33 d
Method: OECD Test Guideline 210
Toxicity to daphnia and other
aquatic invertebrates (Chron ic toxicity)
: NOEC (Daphnia magna (Water flea)): 0.91 mg/l
Exposure time: 21 d
Method: OECD Test Guideline 211
Toxicity to microorganisms : NOEC: 10.3 mg/l
Exposure time: 3 h
Method: OECD Test Guideline 209

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Persistence and degradability
Components:
Indaziflam:
Biodegradability : Result: Not readily biodegradable.
Method: OECD Test Guideline 301F
Remarks: Based on data from similar materials
Propylene glycol:
Biodegradability : Result: Readily biodegradable.
Biodegradation: 98.3 %
Exposure time: 28 d
Method: OECD Test Guideline 301F
Bioaccumulative potential
Components:
Indaziflam:
Bioaccumulation : Species: Lepomis macrochirus (Bluegill sunfish)
Bioconcentration factor (BCF): < 500
Method: OECD Test Guideline 305
Remarks: Based on data from similar materials
Partition coefficient: n octanol/water
: log Pow: 3.7
Propylene glycol:
Partition coefficient: n octanol/water
: log Pow: -1.07
Method: Regulation (EC) No. 440/2008, Annex, A.8
1,2-Benzisothiazol-3(2H)-one:
Bioaccumulation : Species: Lepomis macrochirus (Bluegill sunfish)
Bioconcentration factor (BCF): 6.62
Partition coefficient: n octanol/water
: log Pow: 0.7
Mobility in soil
No data available
Other adverse effects
No data available

SECTION 13. DISPOSAL CONSIDERATIONS
Disposal methods
Waste from residues : It is best to use all of the product in accordance with label

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directions. If it is necessary to dispose of unused product,
please follow container label instructions and applicable local
guidelines.
Do not dispose of waste into sewer.
Contaminated packaging : Follow advice on product label and/or leaflet.
Empty containers retain residue and can be dangerous.
Do not re-use empty containers.

SECTION 14. TRANSPORT INFORMATION
International Regulations
UNRTDG
UN number : UN 3082
Proper shipping name : ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID,
N.O.S.
(Indaziflam)
Class : 9
Packing group : III
Labels : 9
Environmentally hazardous : yes
IATA-DGR
UN/ID No. : UN 3082
Proper shipping name : Environmentally hazardous substance, liquid, n.o.s.
(Indaziflam)
Class : 9
Packing group : III
Labels : Miscellaneous
Packing instruction (cargo
aircraft)
: 964
Packing instruction (passen ger aircraft)
: 964
Environmentally hazardous : yes
IMDG-Code
UN number : UN 3082
Proper shipping name : ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID,
N.O.S.
(Indaziflam)
Class : 9
Packing group : III
Labels : 9
EmS Code : F-A, S-F
Marine pollutant : yes
Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
Not applicable for product as supplied.
National Regulations
ADG

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UN number : UN 3082
Proper shipping name : ENVIRONMENTALLY HAZARDOUS SUBSTANCE, LIQUID,
N.O.S.
(Indaziflam)
Class : 9
Packing group : III
Labels : 9
Hazchem Code : •3Z
Environmentally hazardous : yes
Special precautions for user
The transport classification(s) provided herein are for informational purposes only, and solely
based upon the properties of the unpackaged material as it is described within this Safety Data
Sheet. Transportation classifications may vary by mode of transportation, package sizes, and var iations in regional or country regulations.

SECTION 15. REGULATORY INFORMATION
Safety, health and environmental regulations/legislation specific for the substance or mix ture
Therapeutic Goods (Poisons
Standard) Instrument
: Schedule 6 (Please use the original publication to check for
specific uses, specific conditions or threshold limits that might
apply for this chemical)
Prohibition/Licensing Requirements : There is no applicable prohibition,
authorisation and restricted use
requirements, including for carcino gens referred to in Schedule 10 of
the model WHS Act and Regula tions.
Active substance : 500 g/l
Indaziflam

SECTION 16: ANY OTHER RELEVANT INFORMATION
Further information
Revision Date : 04.10.2024
Sources of key data used to
compile the Safety Data
Sheet
: Internal technical data, data from raw material SDSs, OECD
eChem Portal search results and European Chemicals Agen cy,
Items where changes have been made to the previous version are highlighted in the body of this
document by two vertical lines.
Date format : dd.mm.yyyy
Full text of other abbreviations
AU OEL : Australia. Workplace Exposure Standards for Airborne Con taminants.

19 / 19
AU OEL / TWA : Exposure standard - time weighted average
AIIC - Australian Inventory of Industrial Chemicals; ANTT - National Agency for Transport by
Land of Brazil; ASTM - American Society for the Testing of Materials; bw - Body weight; CMR -
Carcinogen, Mutagen or Reproductive Toxicant; DIN - Standard of the German Institute for
Standardisation; DSL - Domestic Substances List (Canada); ECx - Concentration associated with
x% response; ELx - Loading rate associated with x% response; EmS - Emergency Schedule;
ENCS - Existing and New Chemical Substances (Japan); ErCx - Concentration associated with
x% growth rate response; ERG - Emergency Response Guide; GHS - Globally Harmonized Sys tem; GLP - Good Laboratory Practice; IARC - International Agency for Research on Cancer; IATA
- International Air Transport Association; IBC - International Code for the Construction and
Equipment of Ships carrying Dangerous Chemicals in Bulk; IC50 - Half maximal inhibitory con centration; ICAO - International Civil Aviation Organization; IECSC - Inventory of Existing Chemi cal Substances in China; IMDG - International Maritime Dangerous Goods; IMO - International
Maritime Organization; ISHL - Industrial Safety and Health Law (Japan); ISO - International Or ganisation for Standardization; KECI - Korea Existing Chemicals Inventory; LC50 - Lethal Con centration to 50 % of a test population; LD50 - Lethal Dose to 50% of a test population (Median
Lethal Dose); MARPOL - International Convention for the Prevention of Pollution from Ships;
n.o.s. - Not Otherwise Specified; Nch - Chilean Norm; NO(A)EC - No Observed (Adverse) Effect
Concentration; NO(A)EL - No Observed (Adverse) Effect Level; NOELR - No Observable Effect
Loading Rate; NOM - Official Mexican Norm; NTP - National Toxicology Program; NZIoC - New
Zealand Inventory of Chemicals; OECD - Organization for Economic Co-operation and Develop ment; OPPTS - Office of Chemical Safety and Pollution Prevention; PBT - Persistent, Bioaccumu lative and Toxic substance; PICCS - Philippines Inventory of Chemicals and Chemical Substanc es; (Q)SAR - (Quantitative) Structure Activity Relationship; REACH - Regulation (EC) No
1907/2006 of the European Parliament and of the Council concerning the Registration, Evalua tion, Authorisation and Restriction of Chemicals; SADT - Self-Accelerating Decomposition Tem perature; SDS - Safety Data Sheet; TCSI - Taiwan Chemical Substance Inventory; TDG - Trans portation of Dangerous Goods; TECI - Thailand Existing Chemicals Inventory; TSCA - Toxic Sub stances Control Act (United States); UN - United Nations; UNRTDG - United Nations Recom mendations on the Transport of Dangerous Goods; vPvB - Very Persistent and Very Bioaccumu lative; WHMIS - Workplace Hazardous Materials Information System
The information provided in this Safety Data Sheet is correct to the best of our knowledge, infor mation and belief at the date of its publication. The information is designed only as a guidance for
safe handling, use, processing, storage, transportation, disposal and release and shall not be
considered a warranty or quality specification of any type. The information provided relates only
to the specific material identified at the top of this SDS and may not be valid when the SDS mate rial is used in combination with any other materials or in any process, unless specified in the text.
Material users should review the information and recommendations in the specific context of their
intended manner of handling, use, processing and storage, including an assessment of the ap propriateness of the SDS material in the user’s end product, if applicable.
AU / EN
